Ro 67-7476
CAS No. 298690-60-5
Ro 67-7476 ( —— )
Catalog No. M17468 CAS No. 298690-60-5
Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 39 | In Stock |
|
5MG | 77 | In Stock |
|
10MG | 120 | In Stock |
|
25MG | 244 | In Stock |
|
50MG | 441 | In Stock |
|
100MG | 644 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameRo 67-7476
-
NoteResearch use only, not for human use.
-
Brief DescriptionRo 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.
-
DescriptionRo 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
Target5-HT Receptor
-
RecptormGluR1
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number298690-60-5
-
Formula Weight319.39
-
Molecular FormulaC17H18FNO2S
-
Purity98%
-
SolubilityDMSO : ≥ 40 mg/mL; 125.24 mM
-
SMILESN1([C@@H](CCC1)c1ccc(cc1)F)S(=O)(=O)c1ccc(cc1)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Hemstapat K et al. Mol Pharmacol. 2006 Aug, 70(2), 616-26
molnova catalog
related products
-
BIMU 8
BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.
-
MM 77 dihydrochlorid...
MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.
-
Citalopram HBr
Citalopram hydrobromide belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs).