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Home - Products - Endocrinology/Hormones - 5-HT Receptor - Ro 67-7476

Ro 67-7476

CAS No. 298690-60-5

Ro 67-7476 ( —— )

Catalog No. M17468 CAS No. 298690-60-5

Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 77 In Stock
10MG 120 In Stock
25MG 244 In Stock
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Biological Information

  • Product Name
    Ro 67-7476
  • Note
    Research use only, not for human use.
  • Brief Description
    Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.
  • Description
    Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    mGluR1
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    298690-60-5
  • Formula Weight
    319.39
  • Molecular Formula
    C17H18FNO2S
  • Purity
    98%
  • Solubility
    DMSO : ≥ 40 mg/mL; 125.24 mM
  • SMILES
    N1([C@@H](CCC1)c1ccc(cc1)F)S(=O)(=O)c1ccc(cc1)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hemstapat K et al. Mol Pharmacol. 2006 Aug, 70(2), 616-26
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